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The Genoscope laboratories / UMR8030

DossierBioinformatics Analyses for Genomics and Metabolism

Analyses Bio-Informatiques pour la Génomique et le Métabolisme

The LABGeM (Laboratory of Bioinformatics Analyses for Genomics and Metabolism) is a bioinformatics team of the Genomics Metabolics research unit of the Genoscope. Our activities concern the development of bioinformatics methods and databases for the analysis of prokaryotic genomes and their metabolism: comparative genomics, metagenomics, pangenomics, functional annotation, enzyme family and metabolic network analysis. In addition, we offer to a worldwide community of microbiologists a genome analysis service through the MicroScope platform (>5000 user accounts, >1200 citations). These tools help us make sense of the deluge of genomic data from which the function of many genes remains completely unknown. Several bioanalysis projects are conducted with academic and industrial partners for applications in environmental biology,  biotechnology and health.

Ongoing research activities focus on:
the development of meta-pangenomic approaches to study the diversity of species in various biomes
the exploration of the functional diversity of metabolic pathways and enzyme families from genomic or metagenomic resources.

Scientific platform and equipment
The MicroScope platform is a member of the French Institute of Bioinformatics (IFB) and associated with the France Genomique sequencing infrastructure. The platform is also integrated into the ELIXIR and IBISBA european infrastructures.

The lab  has access to Genoscope's IT infrastructure and to the CEA's very large computing centre at Bruyères-le-Châtel (CCRT).

Quality management
The Quality Management System of the LABGeM team has been certified according to the ISO 9001:2015 and NF X50-900:2016 standards (Lloyd's Register Quality Assurance France S.A.S.). The certification applies to LABGEM activities of research, developments, services and MicroScope training.

Published on 13 July 2022