The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
Researchers from MIRCen (CEA-Jacob) have shown that undetectable proteinaceous aggregates involved in Alzheimer's disease can be transmitted during brain surgeries in an experimental context.
The nuclear power plant accidents at Chernobyl and Fukushima released enormous amounts of radioactive iodine into the atmosphere. Researchers from IRCM (CEA-Jacob) propose an analysis of data on the health consequences of those accidents and particularly the effects they had on the thyroid.
In a recent work published in Frontiers in Microbiology, a team from Genoscope (CEA-Jacob) has shown a role for corrinoids in the degradation of chlorine compounds (such as chlordecone or lindane) by the bacterium Citrobacter sp86. Because their increased production in contaminated environments could accelerate decontamination processes, these corrinoids may lay paths to novel bioremediation applications.
The LSHL (IRCM/CEA-Jacob) and the radiation oncology department of the Lausanne University Hospital teamed to compare FLASH radiotherapy to conventional radiotherapy in the setting of acute lymphoblastic leukemia. Their results, published in the International Journal of Radiation Oncology * Biology * Physics, open new paths to treat this type of leukemia while preserving normal hematopoiesis.
Researchers from IRCM (CEA-Jacob) have identified a DNA sequence polymorphism that leads to reduced production of interferon β by myeloid cells. The substitution, which is present in about 30% of the population, could affect immune response to infections and tumors.
In an article published in Acta Neuropathologica, researchers from SEPIA (CEA-Jacob) reported the discovery of a new mode of prion propagation from a localized contamination.
Since 2017, Genoscope has been involved in energy research. Several engagements within various CEA initiatives (CEA consortium for the SUNRISE project, the 2019 strategic domain NTE, the FCC workgroup for the integrated vision for energy, etc.) position Genoscope as an active participant in the CEA program Circular Carbon Economy (CEE).
The Jean Bernard Prize, named after the founder of the French Foundation for Medical Research (FRM), honors scientists whose research greatens public knowledge in health. This year, the FRM presented the Jean Bernard Prize to Prof. François Desgrandchamps of the Immuno-Hematology Research Unit (CEA-Jacob).
Like many of its counterparts, the CEA is a signatory to scientific integrity charters guaranteeing honesty and rigor in research and higher learning. Within this framework, Elsa Cortijo, director of fundamental research at CEA, has appointed Élisabeth Menu, biologist-immunovirologist at IDMIT, as scientific integrity correspondent for the François Jacob Institute of Biology.
Paris-Saclay University earned the 14th spot among the top 1000 universities in the 2020 edition of the Shanghai Ranking, becoming thus the first French higher learning institute to break into the top-15 regardless of specialties. Of the 35 Paris-Saclay University researchers who were the most cited in their fields, 13 are affiliated with CEA centers and four of those with CEA-Jacob: Jean-Marc Aury, Karine Labadie, Julie Poulain and Patrick Wincker.
IDMIT (CEA-Jacob) is participating in CARE, a public-private consortium of 37 organizations brought together to speed the development of treatments for COVID-19 and future coronavirus epidemics.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.