The François Jacob Institute of Biology brings together five departments and three services
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nearly 700 scientists, the François Jacob Institute of Biology benefits from an
international presence in the fields of imaging, new therapies, radiobiology,
toxicology, infectiology and genomics.
The teams of the IDMIT department are dedicated to studying emerging or re-emerging infectious diseases and their pathophysiology, as well as the interactions between organisms and pathogenic agents such as HIV, chikungunya virus, influenza, and tuberculosis. The teams develop new therapeutic, vaccinal and prophylactic approaches.
Researchers in the IRCM department work on the cellular responses to ionizing radiation and certain toxic substances (nanoparticles, endocrine disruptors, etc.). They are particularly interested in the response of stem cells, as well as the mechanisms of transmitting radiation-induced damage and its long-term consequences.
Multidisciplinary teams design new approaches to gene, cellular and molecular therapies in order to treat inherited blood disorders (such as beta thalassemia and sickle-cell disease) and neurodegenerative diseases (such as Alzheimer's, Parkinson's, and Huntington's diseases). The teams participate in preclinical and clinical trials, as part of a translational research approach to accelerate the transfer of innovations from the laboratory to the patient.
Using their sequencing capabilities and expertise in genome analysis, the teams of the Institute based at Évry can explore biodiversity and interpret the human genome in order to understand human pathologies. They also analyze genomes so as to propose energy-saving synthesis processes (biocatalysis, synthetic biology, etc.) to industry.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.