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The last two years in scientific news
Protein aggregation in neurodegenerative disorders, 2017 (in french with english subtitles)
France Parkinson : Molecular basis of selective propagation of alpha-synuclein aggregates in the central nervous system in Parkinson’s disease
Coups d'Elan pour la Recherche Française 2011, Bettencourt Schueller foundation award, Ronald Melki
Great scientific prize 2016 from the foundation Simone and Cino Del Duca – Institut de France, Ronald Melki
For a complete list of publications, click here.
Atomic Force Microscopy Imaging and Nanomechanical Properties of Six Tau Isoform Assemblies.
Makky A, Bousset L, Madiona K, Melki R.
Biophys J. 2020 Nov 18:S0006-3495(20)30893-6.
The structural differences between patient-derived
α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies. Van der Perren A, Gelders G, Fenyi A, Bousset L, Brito F, Peelaerts W, Van den Haute C, Gentleman S, Melki R,
Baekelandt V. Acta Neuropathol. 2020 Jun;139(6):977-1000.
Differential Membrane Binding and Seeding of Distinct α-Synuclein Fibrillar Polymorphs.
Shrivastava AN, Bousset L, Renner M, Redeker V, Savistchenko J, Triller A, Melki R. Biophys J. 2020 Mar 24;118(6):1301-1320.
α-Synuclein conformational strains spread, seed and target neuronal cells differentially after injection into the olfactory bulb.
Rey NL, Bousset L, George S, Madaj Z, Meyerdirk L, Schulz E, Steiner JA, Melki R, Brundin P.Acta Neuropathol Commun. 2019 Dec 30;7(1):221.
Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Guerrero-Ferreira R, Taylor NM, Arteni AA, Kumari P, Mona D, Ringler P, Britschgi M, Lauer ME, Makky A, Verasdonck J, Riek R, Melki R, Meier BH, Böckmann A, Bousset L, Stahlberg H.Elife. 2019.
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