The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
Find here all the scientific news and highlights about the François Jacob Institute of Biology.
With massively parallel sequencing of DNA collected from the surfaces of the earth's oceans and seas (Tara Oceans expeditions) and more than ten years of analysis, an international team piloted by researchers from Genoscope (CEA-Jacob) and the CNRS has solved one of environmental biology's greatest puzzles.
A team of researchers from IRCM (CEA-Jacob) and I2BC have shed light on the role of ComFC, a bacterial protein involved in natural transformation, itself a driving mechanism for the propagation of antibiotic resistance genes and virulence factors.
In an article published in Cell Reports, an international team including researchers from MIRCen showed that a cerebral network associated with highly elaborate cognitive capacities in humans differs from the comparable network in non-human primates.
A preclinical multimodal imaging study conducted by the Neurodegenerative Diseases Laboratory (LMN/MIRCen) and published in Human Molecular Genetics has shed light on cerebral alterations in Huntington's disease.
Working from 35,000 worldwide water and plankton samples collected by the Tara Oceans Expeditions and sequenced by Genoscope,, an international team of researchers has identified 5,500 new RNA virus species and met the challenge of their phylogenetic classification. The team's work was published in Science.
In a new study published in Brain, researchers MIRCen used mouse models of Huntington's disease to show that stimulating reactive astrocyte formation favors the elimination of mutant huntingtin protein, reducing both the quantity and size of the aggregates.
The Epigenetic and Environment Laboratory (CNRGH) was part of a study that characterized associations between placental DNA methylation and the concentrations of 11 phthalate-derived metabolites in urine samples from pregnant women. The samples used for the analysis, published in Environment International, were obtained from EDEN, a cohort of French mothers and children.
As part of a international partnership, researchers from SRHI have shown that Crispr/Cas9 can be used to inactivate HLA-G expression in human cancer cell lines. Their unprecedented findings, published in Scientific Reports, suggest the possibility of novel treatment strategies to supplement current tumor immunotherapies.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.