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A new model for the study of bacterial metabolism
After an extensive inventory of species described in the literature, we noticed that the species Acinetobacter baylyi, which was isolated from soil, presents real advantages as a model for the study of bacterial metabolism. A. baylyi has the highest capacity for transformation by exogenous DNA (natural competence (1)).
of any micro-organism. This property, associated with its capacity to undergo homologous recombination (2), makes genetic modification very easy. This is a process of targeted exchange (directed mutagenesis) which permits specific modification of genetic information at a given locus.
An analytic phase will now be undertaken in the collection, in addition to systematic phenotyping in order to study, for example, genes with unknown function which co-localize with genes which participate in the same metabolic pathway.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.