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MRI imaging

Biologie moléculaire et production virale

Published on 29 September 2021

​Nuclear magnetic resonance imaging of the central nervous system


High-resolution imaging techniques and multinuclear  spectroscopy are being developed and validated with a 7T magnet:

  • Optimized NMR sequences for rodents and primates (T1, T2 and T2* weighting).
  • Optimized NMR sequences for 1H, 13C and 31P cerebral spectroscopy in rodents and primates, automated quantification of short-echo time spectra.
  • ZTE (Zero Echo Time) sequence for oxygen-17 imaging.
  • CEST ("Chemical Exchange Saturation Transfer") imaging of glutamate in rodents.
  • Diffusion-weighted NMR spectroscopy sequences
  • Other sequences can be optimized in the framework of collaborative projects.


Examinations can be carried out on rodents and primates in biosafety level 1, 2 or 3 confinement. The magnet is sealed in a hermetic sarcophagus, making it possible to carry out maintenance interventions on the magnet in confinement conditions.

A magnetic resonance imaging experiment on the 11.7Tesla preclinical MRI machine at MIRCen (courtesy of P. Stroppa/CEA).


  • Horizontal 7 T magnet (Bruker) dedicated to primates, with radiofrequency coils optimized for the brain and spinal cord of primates.
  • Horizontal 11.7 T magnet (Bruker) for imaging in rodents (funded by NeuraTRIS) equipped with a cryoprobe.