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IRCM Publications

Published on 2 July 2018
A R-loop sensing pathway mediates the relocation of transcribed genes to nuclear pore complexes.
Penzo A, Dubarry M, Brocas C, Zheng M, Mangione RM, Rougemaille M, Goncalves C, Lautier O, Libri D, Simon MN, Géli V, Dubrana K, Palancade B.
All roads lead to MRN regulation at telomeres: different paths to one solution.
Roisné-Hamelin F & Marcand S
Congenital mirror movements are associated with defective polymerization of RAD51.
Trouillard O., Dupaigne P., Dunoyer M., Doulazmi M., Herlin M.K., Frismand S., Riou A., Legros V., Chevreux G., Veaute X., Busso D., Fouquet C., Saint-Martin C., Ménetret A., Trembleau A., Dusart I., Dubacq C., Roze E.
DOT1L regulates chromatin reorganization and gene expression during sperm differentiation.
Blanco M, El Khattabi L, Gobé C, Crespo M, Coulée M, de la Iglesia A, Ialy-Radio C, Lapoujade C, Givelet M, Delessard M, Seller-Corona I, Yamaguchi K, Vernet N, Van Leeuwen F, Lermine A, Okada Y, Daveau R, Oliva R, Fouchet P, Ziyyat A, Pflieger D, Cocquet J.
In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis.
Matos-Rodrigues G, Barroca V, Muhammad AA, Dardillac E, Allouch A, Koundrioukoff S, Lewandowski D, Despras E, Guirouilh-Barbat J, Frappart L, Kannouche P, Dupaigne P, Le Cam E, Perfettini JL, Romeo PH, Debatisse M, Jasin M, Livera G, Martini E & Lopez BS.
A biobank of pediatric patient-derived-xenograft models in cancer precision medicine trial MAPPYACTS for relapsed and refractory tumors
Marques Da Costa ME, Zaidi S, Scoazec JY, Droit R, Lim WC, Marchais A, Salmon J, Cherkaoui S, Morscher RJ, Laurent A, Malinge S, Mercher T, Tabone-Eglinger S, Goddard I, Pflumio F, Calvo J, Redini F, Entz-Werlé N, Soriano A, Villanueva A, Cairo S, Chastagner P, Moro M, Owens C, Casanova M, Hladun-Alvaro R, Berlanga P, Daudigeos-Dubus E, Dessen P, Zitvogel L, Lacroix L, Pierron G, Delattre O, Schleiermacher G, Surdez D, Geoerger B.
Beta-Catenin and its new partner FOXO3 shake T-ALL
Julien Calvo, Françoise Pflumio
Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells
D’Augustin, O., Gaudon, V., Siberchicot, C., Smith, R., Chapuis, C., Depagne, J., Veaute, X., Busso, D., Di Guilmi, A.M., Castaing, B., Radicella, J.P., Campalans, A.*, Huet, S* (co-corresponding authors)
Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps
Maloisel L., Ma E., Phipps J., Deshayes A., Mattarocci S., Marcand S., Dubrana K., Coïc E.
Deciphering the immune reaction leading to spontaneous melanoma regression: initial role of MHCII+ CD163- macrophages
Blanc F, Bertho N, Piton G, Leplat JJ, Egidy G, Bourneuf E, Vincent-Naulleau S, Prévost-Blondel A
Spatio-temporal dynamics of the DNA glycosylase OGG1 in finding and processing 8-oxoguanine
Cintori, L., Di Guilmi, A.M., Canitrot, Y., Huet, S., Campalans, A
The Antioxidant TEMPOL Protects Human Hematopoietic Stem Cells From Culture-Mediated Loss of Functions
Elia Henry, Frédéric Picou, Vilma Barroca, Nathalie Dechamps, Steicy Sobrino, Emmanuelle Six, Camille Gobeaux, Patrick Auberger, Olivier Hérault, Françoise Pflumio, Marie-Laure Arcangeli
Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis
Corentin Bernou, Marc-André Mouthon, Mathieu Daynac, Benjamin Demaille, Vilma Barroca, Sébastien Couillard-Despres, Nathalie Déchamps, Véronique Ménard, Léa Bellenger, Christophe Antoniewski, Alexandra Chicheportiche, François D. Boussin
A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner.
Ragu S, Droin N, Matos-Rodrigues G, Barascu A, Caillat S, Zarkovic G, Siberchicot C, Dardillac E, Gelot C, Guirouilh-Barbat J, Radicella JP, Ishchenko AA, Ravanat JL, Solary E, Lopez BS
Chelation therapy with 3,4,3-Li(1,2-HOPO) after pulmonary exposure to plutonium in rats.
Grémy O, Devilliers K, Miccoli L
Melanophages give rise to hyperreflective foci in AMD, a disease-progression marker
Augustin S, Lam M, Lavalette S, Verschueren A, Blond F, Forster V, Przegralek L, He Z, Lewandowski D, Bemelmans AP, Picaud S, Sahel JA, Mathis T, Paques M, Thuret G, Guillonneau X, Delarasse C, Sennlaub F
Ovarian tissue cryopreservation can be combined simultaneously with oocyte retrieval after controlled ovarian hyperstimulation.
Puy V, Dupeux M, Mayeur A, Grynberg M, Benoit A, Bendayan M, Zhegari F, Hesters L, Gallot V, Prevot S, Frydman N, Sonigo C
Take a Swipe at Actinide Bioavailability: Application of a New In Vitro Method.
Griffiths NM, Moureau A, Coudert S, Huet F, Defrance M, Van der Meeren A
The neural addiction of cancer.
Magnon C, Hondermarck H
XLF/Cernunnos loss impairs mouse brain development by altering symmetric proliferative divisions of neural progenitors.
Bery A, Etienne O, Mouton L, Mokrani S, Granotier-Beckers C, Gauthier LR, Feat-Vetel J, Kortulewski T, Pérès EA, Desmaze C, Lestaveal P, Barroca V, Laugeray A, Boumezbeur F, Abramovski V, Mortaud S, Menuet A, Le Bihan D, Villartay JP, Boussin FD
Polymerase iota (Pol ?) prevents PrimPol-mediated nascent DNA synthesis and chromosome instability
Sabrina F Mansilla1, Agostina P Bertolin, Sofía Venerus Arbilla, Bryan A Castaño, Tiya Jahjah, Jenny K Singh, Sebastián O Siri, María Victoria Castro, María Belén de la Vega, Annabel Quinet, Lisa Wiesmüller, Vanesa Gottifredi
Requirement of transcription-coupled nucleotide excision repair for the removal of a specific type of oxidatively induced DNA damage.
Sarmini, L., Meabed, M., Emmanouil, E., Atsaves, G., Robeska, E., Karwowski, B.T., Campalans, A., Gimisis, T., Khobta, A.
Foetal exposure to the bisphenols BADGE and BPAF impairs meiosis through DNA oxidation in mouse ovaries
Abdallah, S., Jampy, A., Moison, D., Wieckowski, M., Messiaen, S., Martini, E., Campalans, A., Radicella, JP., Rouiller-Fabre, V., Livera, G., Guerquin, MJ
Loss of CD24 promotes radiation? and chemo?resistance by inducing stemness properties associated with a hybrid E/M state in breast cancer cells
Bontemps, I., Lallemand, C., Biard, D., Déchamps, N., Kortulewski, T., Bourneuf, E., Siberchicot, C., Boussin, F., Chevillard, S., Campalans, A., Lebeau, J.
OGG1 at the crossroads between repair and transcriptional regulation
Di Guilmi, A., Fonknechten, N., Campalans, A.
OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression
Tanushi X., Pinna G., Vandamme M., Siberchicot C., D'Augustin O., Di Guilmi AM, Radicella JP., Castaing B., Smith R., Huet S., Leteurtre F.,  Campalans A.
53BP1: Keeping It under Control, Even at a Distance from DNA Damage.
Rass E, Willaume S, Bertrand P
A role for endothelial alpha-mannosidase MAN1C1 in radiation-induced immune cell recruitment
Ladaigue S, Lefranc AC, Balde K, Quitoco M, Bacquer E, Busso D, Piton G, Dépagne J, Déchamps N, Yamakawa N, Debusschere L, Han C, Allain F, Buard V, Tarlet G, François A, Paget V, Milliat F, Guipaud O
A Simple, Rapid, Comparative Evaluation of Multiple Products for Decontamination of Actinide-contaminated Rat Skin Ex Vivo.
Griffiths NM, Devilliers K, Laroche P, Van der Meeren A
Breakage in breakage-fusion-bridge cycle: an 80-year-old mystery.
Guérin TM , Marcand S
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