 | | High caspase 3 and vulnerability to dual BCL2 family inhibition define ETO2::GLIS2 pediatric leukemia | Aid Z, Robert E, Lopez CK, Bourgoin M, Boudia F, Le Mene M, Riviere J, Baille M, Benbarche S, Renou L, Fagnan A, Thirant C, Federici L, Touchard L, Lecluse Y, Jetten A, Geoerger B, Lapillonne H, Solary E, Gaudry M, Meshinchi S, Pflumio F, Auberger P, Lobry C, Petit A, Jacquel A, Mercher T
| | 2022 | | | | CDKN1A is a target for phagocytosis-mediated cellular immunotherapy in acute leukemia | Allouch A, Voisin L, Zhang Y, Syed R, Lecluse Y, Calvo J, Sélimoglu-Buet D, De Botton S, Louache F, Pflumio F, Solary E, Perfettini JL
| | 2022 | | | | REDD1 is a gatekeeper of murine hematopoietic stem cell functions during stress responses | Barroca V, Henry E, Dechamps N, Renou L, Chaintreuil P, Kulkarni R, Devanand S, Jacquel A, Robert G, Auberger P, Pflumio F, Arcangeli ML
| | 2022 | | | | Hypoxia favors chemoresistance in T-ALL through a HIF1-mediated mTORC1 inhibition loop | L Fahy, J Calvo, S Chabi, L Renou, C Le Maout, S Poglio, T Leblanc, A Petit, A Baruchel, P Ballerini, I Naguibneva, R Haddad, ML Arcangeli, F Mazurier, F Pflumio* and B Uzan | | 2021 | | | | Desperately seeking a home marrow niche for T-cell acute lymphoblastic leukaemia. | Calvo J, Fahy L, Uzan B, Pflumio F. | | 2019 | | | | Combined G-CSF and Plerixafor enhance hematopoietic recovery of CD34+ cells from poor mobilizer patients in NSG mice. | Arcangeli ML, Brault P, Bourhis JH, Kuhnowski F, Henry E, Barroca V et al. | | 2020 | | | | Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia. | Zhou Y, Han C, Wang E, Lorch AH, Serafin V, Cho B-K et al. | | 2020 | | | | Ultra-high dose rate FLASH and conventional dose rate irradiation differentially affect human acute lymphoblastic leukemia and normal hematopoiesis. | Chabi S, Hong Van To T, Leavitt R, PhD4, Poglio S, Gonçalves Jorge P , Jaccard M, PeterssonK, Petit B, Roméo, PH, Pflumio,F, Vozenin, MC and Uzan, B | | 2020 | | | | Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations | Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli | | 2020 | | | | A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation. | Roos-Weil D, Decaudin C, Armand M, Della-Valle V, Diop MK, Ghamlouch H, Ropars V, Hérate C, Lara D, Durot E, Haddad R, Mylonas E, Damm F, Pflumio F, Stoilova B, Metzner M, Elemento O, Dessen P, Camara-Clayette V, Cosset F-L, et al | | 2019 | | | | Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples. | Labarthe L, Henriquez S, Lambotte O, Di Santo JP, Le Grand R, Pflumio F, Arcangeli M-L, Legrand N & Bourgeois C | | 2019 | | | | Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors. | Chabi S, Uzan B, Naguibneva I, Rucci J, Fahy L, Calvo J, Arcangeli M-L, Mazurier F, Pflumio F & Haddad R | | 2019 | | | | Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia. | Lopez CK, Noguera E, Stavropoulou V, Robert E, Aid Z, Ballerini P, Bilhou-Nabera C, Lapillonne H, Boudia F, Thirant C, Fagnan A, Arcangeli M-L, Kinston SJ, Diop M, Job B, Lecluse Y, Brunet E, Babin L, Villeval JL, Delabesse E, et al | | 2019 | | | | T-cell acute lymphoblastic leukemia displays autocrine production of Interleukin-7. | Buffière A, Uzan B, Aucagne R, Hermetet F, Mas M, Nassurdine S, Aznague A, Carmignac V, Tournier B, Bouchot O, Ballerini P, Barata J-T, Bastie J-N, Delva L, Pflumio F, Quéré R | | 2019 | | | | Epigenetic silencing affects L-asparaginase sensitivity and predicts outcome in T-ALL | Touzart A, Lengline E, Latiri M, Belhocine M, Smith C, Thomas X, Spicuglia S, Puthier D, Pflumio F, Leguay T, Graux C, Chalandon Y, Huguet F, Leprêtre S, Ifrah N, Dombret H, Macintyre E, Hunault-Berger M, Boissel N, Asnafi V. | | 2019 | | | | Saracatinib impairs maintenance of human T-ALL by targeting the LCK tyrosine kinase in cells displaying high level of lipid rafts. | Buffière A, Accogli T, Saint-Paul L, Lucchi G, Uzan B, Ballerini P, Bastie J-N, Delva L, Pflumio F, Quéré R | | 2018 | | | | Single-cell analysis reveals the continuum of human lympho-myeloid progenitor cells | Karamitros D, Stoilova B, Aboukhalil Z, Hamey F, Reinisch A, Samitsch M, Quek L, Otto G, Repapi E, Doondeea J, Usukhbayar B, Calvo J, Taylor S, Goardon N, Six E, Pflumio F, Porcher C, Majeti R, Gottgens B, Vyas P | | 2018 | | | | Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia | Cahu X, Calvo J, Poglio S, Prade N, Colsch B, Arcangeli ML, Leblanc T, Petit A, Baleydier F, Baruchel A, Landman-Parker J, Junot C, Larghero J, Ballerini P, Delabesse E, Uzan B, Pflumio F | | 2017 | | | | Bone Marrow Hematons: An Access Point to the Human Hematopoietic Niche | Janel A, Berger J, Bourgne C, Lemal R, Boiret-Dupre N, Dubois-Galopin F, Dechelotte P, Bothorel C, Hermet E, Chabi S, Bay JO, Lambert C, Pereira B, Pflumio F, Haddad R, Berger MG | | 2017 | | | | ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia | Thirant C, Ignacimouttou C, Lopez CK, Diop M, Le Mouel L, Thiollier C, Siret A, Dessen P, Aid Z, Riviere J, Rameau P, Lefebvre C, Khaled M, Leverger G, Ballerini P, Petit A, Raslova H, Carmichael CL, Kile BT, Soler E, Crispino JD, Wichmann C, Pflumio F, Schwaller J, Vainchenker W, Lobry C, Droin N, Bernard OA, Malinge S, Mercher T | | 2017 | | | | Homeobox protein TLX3 activates miR-125b expression to promote T-cell acute lymphoblastic leukemia | Renou L, Boelle PY, Deswarte C, Spicuglia S, Benyoucef A, Calvo J, Uzan B, Belhocine M, Cieslak A, Landman-Parker J, Baruchel A, Asnafi V, Pflumio F, Ballerini P, Naguibneva I | | 2017 | | | | PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells | Naudin C, Hattabi A, Michelet F, Miri-Nezhad A, Benyoucef A, Pflumio F, Guillonneau F, Fichelson S, Vigon I, Dusanter-Fourt I, Lauret E | | 2017 | | | | Stem Cell Leukemia: how a TALented actor can go awry on the hematopoietic stage | Correia NC, Arcangeli ML, Pflumio F, Barata JT. | | 2016 | | | | Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes. | Chesnais V, Arcangeli ML, Delette C, Rousseau A, Guermouche H, Lefevre C, Bondu S, Diop M, Cheok M, Chapuis N, Legros L, Raynaud S, Willems L, Bouscary D, Lauret E, Bernard OA, Kosmider O, Pflumio F, Fontenay M. | | 2016 | | | | DNMT3A mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice. | Scourzic L, Couronne L, Pedersen MT, Della Valle V, Diop M, Mylonas E, Calvo J, Mouly E, Lopez CK, Martin N, Fontenay M, Bender A, Guibert S, Dubreuil P, Dessen P, Droin N, Pflumio F, Weber M, Gaulard P, Helin K, Mercher T, Bernard OA. | | 2016 | | | | Speed of leukemia development and genetic diversity in xenograft models of T cell Acute Lymphoblastic Leukemia. | Poglio S, Lewandowski D, Calvo J, Caye A, Gros A, Laharanne E, Leblanc T, Landman-Parker J, Baruchel A, Soulier J, Ballerini P, Clappier E, Pflumio F. | | 2016 | | | | Triggering the TCR Developmental Checkpoint Activates a Therapeutically Targetable Tumor Suppressive Pathway in T-cell Leukemia. | Trinquand A, Dos Santos NR, Tran Quang C, Rocchetti F, Zaniboni B, Belhocine M, Da Costa de Jesus C, Lhermitte L, Tesio M, Dussiot M, Cosset FL, Verhoeyen E, Pflumio F, Ifrah N, Dombret H, Spicuglia S, Chatenoud L, Gross DA, Hermine O, Macintyre E, Ghysdael J, Asnafi V. | | 2016 | | | | UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia. | Benyoucef A, Palii CG, Wang C, Porter CJ, Chu A, Dai F, Tremblay V, Rakopoulos P, Singh K, Huang S, Pflumio F, Hebert J, Couture JF, Perkins TJ, Ge K, Dilworth FJ, Brand M. | | 2016 | | | | Rapid childhood T-ALL growth in xenograft models correlates with mature phenotype and NF-kappa B pathway activation but not with poor prognosis. | Poglio S, Cahu X, Uzan B, Besnard-Guerin C, Lapillonne H, Leblanc T, Baruchel A, Landman-Parker J, Petit A, Baleydier F, Amsellem S, Baud V, Ballerini P, Pflumio F. | | 2015 | | | | The SCL/TAL1 transcription factor represses the stress protein DDiT4/REDD1 in human hematopoietic stem/progenitor cells. | Benyoucef A, Calvo J, Renou L, Arcangeli ML, van den Heuvel A, Amsellem S, Mehrpour M, Larghero J, Soler E, Naguibneva I, Pflumio F. | | 2015 | |
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