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The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
A year and a half after the publication of the complete sequence of the pedunculated oak genome by a national consortium led by INRAE and CEA (Genoscope), the first results based on this genomic resource are the subject of a series of articles published on 16 April 2020 in the journal New Phytologist.
Through an international collaboration, researchers from the LRTS laboratory (IRCM/CEA-Jacob) have characterized the cellular and molecular events regulating the balance between fibrotic repair and tissue regeneration and have identified a key player in this balance : macrophages. This study, published in Science Advances, opens up a new therapeutic perspective for the treatment of pathological tissue lesions.
The FRM has just selected eight research projects in its call for projects on the fundamental mechanisms of Alzheimer's disease. A financial contribution of up to 600,000 euros has been allocated to fund the salaries, equipment and operating costs for each project for a period of 2 to 3 years. Among the funded projects, a project led by SEPIA (CEA-Jacob), Genoscope (CEA-Jacob) and ENS-Saclay, focuses on the use of cerebral organoids or 'mini-brains' as a model for the study of Alzheimer's disease.
As soon as the Government announced that the pandemic had reached stage 3 and that the national containment system would be implemented, CEA mobilized to maintain its essential functions, while helping to combat the spread of the virus and protect the health of its 20,000 employees.
A study led by IMVA-HB/IDMIT researchers, published in NPJ Vaccines, has shown the influence of the delay between vaccinations (primary and booster) on the specific humoral immune response. This work also suggests the establishment of a trained immune memory.
Researchers from the SEPIA (CEA)-Sup'Biotech partnership laboratory and the Gly-CRRET (UPEC) laboratory have developed a genetic tool for the long-term expression of proteins in human brain organoids. This work, published in Frontiers in Cellular Neuroscience, concerns the modelling of a genetic form of frontotemporal dementia, a neurodegenerative disease with a tauopathic side similar to Alzheimer's disease.
As a part of the Covid-19 Flash call launched on March 6, 2020, the ANR selected 86 research projects for immediate funding, covering a large number of issues related to the Covid-19 epidemic. Among the selected projects, one project coordinated by Roger Le Grand (IDMIT) focuses on the study of the pathogenesis of the SARS-Cov-2 infection in a pre-clinical study model.
On November 17, 2020, the Life Sciences invite you to their second edition of Meet My Platform | Paris-Saclay University, co-organized with Genopole. Come and discover the potential of technology platforms at Paris-Saclay University. 113 academic platforms and 20 industrial sponsors meet in a dedicated area. Among the speakers of the day, Jean-François Deleuze will present the Centre de Référence d'Innovation et d'Expertise (CRefIX) that he manages, and how this structure allows the development of sequencing protocols for the medicine of the future.
A better understanding of COVID-19 and its spread is essential in order to detect the disease, treat and protect patients. This is why on 30 January 2020, the European Commission launched a request for expressions of interest entitled 'SC1-PHE-CORONAVIRUS-2020: Advancing knowledge for the clinical and public health response to the [COVID-19] epidemic' with a budget of €47.5 million. 17 research projects were shortlisted for funding following evaluation.
With the support of the Ministry of Solidarity and Health and the Ministry of Higher Education, Research and Innovation, 20 scientific initiatives were selected by REACTing's scientific board and presented at a press conference on 11 March. Among them, IDMIT is piloting a fundamental research project on the evolution of Covid-19 in a specific pre-clinical study model.
Event | Crédit Agricole Massy-Palaiseau - 44 bis rue de la Division Leclerc - Massy
On November 17, 2020, the Life Sciences invite you to their second edition of Meet My Platform | Paris-Saclay University, co-organized with Genopole. Come and discover the potential of technology platforms at Paris-Saclay University. 113 academic platforms and 20 industrial sponsors meet in a dedicated area.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.