To access all features of this site, you must enable Javascript. Here are the instructions for enabling Javascript in your web browser.
To carry out their activities, Research Teams of the Frédéric Joliot Institute for Life Sciences have developed high-profile technological platforms in many areas : biomedical imaging, structural biology, metabolomics, High-Throughput screening, level 3 microbiological safety laboratory...
All the news of the Institute of life sciences Frédéric Joliot
A team from BioMaps (SHFJ), in partnership with the Gustave Roussy Institute, has used immunoPET imaging to assess the influence of tissue distribution on the efficacy of cancer immunotherapy, administered intra-tumor and intravenously in mice. Intratumoral administration is more effective and reduces overall exposure of organs at risk
A NeuroSpin team has built a predictive model for the onset of psychosis using a combination of supervised learning analyses and a model of neuroanatomical age, based on neuroimaging data from healthy subjects and those at risk of psychotic transition.
A team from NeuroSpin has recently published 3 papers that address the question of how we perceive time from a cognitive neuroscience perspective, using real-life temporal experiments, laboratory experiments and MEG brainwave measurements indicative of the passage of time, and that shed light on how the brain constructs our experience of lived time.
Researchers at NeuroSpin have recently published 3 articles in Magnetic Resonance in Medicine on their technological and methodological developments that will help meet the challenges of ultra-high field MRI for tomorrow's medical brain imaging.
NeuroSpin researchers map chimpanzee brain structural connectivity for the first time using diffusion MRI data. New image processing enabled them to create two atlases of deep and superficial white matter connectivity. A step towards a better understanding of the evolution of the hominid brain.
In a study published in Nature Communications, researchers from UNICOG and BAOBAB use high-field functional MRI to reveal the brain areas where the representations of quantities generated by a mental arithmetic operation are encoded.
In an article published in Nature Communications, researchers from the I2BC show that applying a fragmentation strategy to the protein partners of assemblies depending on intrinsically disordered regions very significantly improves AlphaFold2's prediction capacity.
Teams from SCBM and SIMoS (DMTS) have developed nano-micelles for the vectorization of an active principle which regulates cholesterol metabolism towards atherosclerotic lesions.
Researchers at the LIAA (SPI/DMTS) have shown that pre- and perinatal exposure of mice to titanium dioxide increases the risk of developing a food allergy, particularly in males.
A collaborative study between SPI and a team from Hôpital Louis Mourier demonstrates the contribution of liquid chromatography coupled with mass spectrometry to the day-to-day analytical needs of a clinical laboratory. Application to the rapid quantification of biomarkers in acute hepatic porphyrias.
Les dispositifs tels que les lampes et les lunettes stroboscopiques censés faciliter la lecture des personnes dyslexiques n’auarient en fait aucun impact. C’est ce que révèle une étude menée par une équipe d’UNICOG (NeuroSpin) et publiée dans la revue Proceedings Royal Society.
Des chercheurs du SIMoS montrent que la combinaison de deux approches in silico et in vitro permet de sélectionner des anticorps thérapeutiques dont la fonctionnalité est préservée tout en diminuant le risque qu’ils induisent une réponse immunitaire indésirable.
I2BC researchers show that the Rif1 protein restrains the replication program and the recruitment of replication initiation factors during early embryonic divisions in X laevis. A step towards elucidating the molecular mechanisms involved in diseases resulting from Rif1 mutations in humans
The CEA is revealing a series of in vivo human brain images acquired with the Iseult MRI machine and its unmatched 11.7 teslas magnetic field strength. This success is the fruit of more than 20 years of R&D as part of the Iseult project, with one pillar goal being to design and build the world’s most powerful MRI machine. Its ambition is to study healthy and diseased human brains with an unprecedented resolution, allowing us to discover new details relating to the brain’s anatomy, connections, and activity.
In an article in the New York Times, Stanislas Dehaene (NeuroSpin director) and Mathias Sablé-Meyer (PhD student) discuss recent results obtained in collaboration with the Collège de France, the CNRS and the University of Paris 8 that show that humans have a universal capacity to understand abstract geometric concepts.
September 2021, the 11.7 Tesla MRI of the Iseult project, the most powerful in the world for human imaging, has just unveiled its first images.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.