The François Jacob Institute of Biology brings together five departments and three services
The last two years in scientific news
Find here all the scientific news and highlights about the François Jacob Institute of Biology.
In a study published in Nature Biomedical Engineering, a team from the Genomics and Radiobiology of Keratinopoiesis laboratory (LGRK/ IRCM) has shown that a transcription factor, KLF4, plays a key role in the proliferation of the stem cells in the epidermis. The discovery brings new therapeutic perspectives to regenerative medicine.
MIRCen contributed to a study that showed that the use of histocompatible neuronal grafts did not eliminate the need for immunosuppressive drugs in a primate model. Those results provide important knowledge for the clinical use of certain cell therapies under development for the treatment of neurodegenerative diseases.
MIRCen researchers have shown that the intracerebral injection of Alzheimer brain extracts into a primate induces lesions typical of the disease and neurodegenerative processes associated with memory loss.
As part of an international study, Genoscope participated in the sequencing of the garden pea genome. That work, published in Nature Genetics, will contribute to improving the agronomic characteristics of this grain legume.
With 3D histology, researchers from MIRCen highlighted, among nine methods of neuroinflammation PET quantification methods, the optimal performances of one of them.
Genoscope contributed to a study describing a novel synthesized nucleic acid with a previously undescribed molecular backbone. This new genetic support expands the biotech armamentarium for tomorrow's medicine.
Researchers from Genoscope have identified about twenty transformation products resulting from the degradation of chlordecone (a compound classed as a persistent organic pollutant) and furthermore demonstrated their presence in French West Indies soils.
Researchers from STI have developed a new generation of lentivirus, paving the way for the use of Mauritian cynomolgus macaque as a pre-clinical study model for the development of new gene therapy products.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.