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Publications du LRIG

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Publié le 18 octobre 2017

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Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity.
Celma L, Corbinais C, Vercruyssen J, Veaute X, de la Sierra-Gallay IL, Guérois R, Busso D, Mathieu A, Marsin S, Quevillon-Cheruel S, Radicella JP.
2017
Incorporating interaction networks into the determination of functionally related hit genes in genomic experiments with Markov random fields.
Robinson S, Nevalainen J, Pinna G, Campalans A, Radicella JP, Guyon L
2017
ComB proteins expression levels determine Helicobacter pylori competence capacity.
Corbinais C, Mathieu A, Damke PP, Kortulewski T, Busso D, Prado-Acosta M, Radicella JP, Marsin S.
2017
Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmium.
Bravard A, Campalans A, Vacher M, Gouget B, Levalois C, Chevillard S, Radicella JP.
2010
A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis
Saintigny Y, Chevalier F, Bravard A, Dardillac E, Laurent D, Hem S, Dépagne J, Radicella JP2, Lopez BS
2016
Following transforming DNA in Helicobacter pylori from uptake to expression
Corbinais C, Mathieu A, Kortulewski T, Radicella JP, Marsin S
2016
XPC deficiency is related to APE1 and OGG1 expression and function
de Melo JT, de Souza Timoteo AR, Lajus TB, Brandão JA, de Souza-Pinto NC, Menck CF, Campalans A, Radicella JP, Vessoni AT, Muotri AR,Agnez-Lima LF
2016
Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function
Damke PP, Dhanaraju R, Marsin S, Radicella JP, Rao DN
2016
Phi-score: A cell-to-cell phenotypic scoring method for sensitive and selective hit discovery in cell-based assays.
Guyon L, Lajaunie C, Fer F, Bhajun R, Sulpice E, Pinna G, Campalans A, Radicella JP, Rouillier P, Mary M,Combe S, Obeid P, Vert JP, Gidrol X
2015
E2F1 and E2F2 induction in response to DNA damage preserves genomic stability in neuronal cells.
Castillo DS, Campalans A, Belluscio LM, Carcagno AL, Radicella JP, Cánepa ET, Pregi N
2015
Interaction with OGG1 is required for efficient recruitment of XRCC1 to base excision repair and maintenance of genetic stability after exposure to oxidative stress
Campalans A, Moritz E, Kortulewski T, Biard D, Epe B, Radicella JP
2015
The nuclease activities of both the Smr domain and an additional LDLK motif are required for an efficient anti-recombination function of Helicobacter pylori?MutS2
Damke PP, Dhanaraju R, Marsin S, Radicella JP, Rao DN
2015
The prion protein is critical for DNA repair and cell survival after genotoxic stress
Bravard A, Auvré F, Fantini D, Bernardino-Sgherri J, Sissoëff L, Daynac M, Xu Z, Etienne O, Dehen C, Comoy E, Boussin FD, Tell G, Deslys JP, Radicella JP.
2015
Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation.
Sonzogni SV, Ogara MF, Castillo DS, Sirkin PF, Radicella JP, Canepa ET
2014
hOGG1-Cys326 variant cells are hypersensitive to DNA repair inhibition by nitric oxide
Moritz E, Pauly K, Bravard A, Hall J, Radicella JP, Epe B
2014
Replication fork collapse is a major cause of the high mutation frequency at three-base lesion clusters
Sedletska Y, Radicella JP, Sage E
2013
Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair
Campalans A, Kortulewski T, Amouroux R, Menoni H, Vermeulen W, Radicella JP
2013
Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments
Fantini D, Moritz E, Auvre F, Amouroux R, Campalans A, Epe B, Bravard A, Radicella JP
2013
Biochemical and Cellular Characterization of Helicobacter pylori RecA, a Protein with High-Level Constitutive Expression
Orillard E, Radicella J P, Marsin S
2011
Unexpected Role for Helicobacter pylori DNA Polymerase I As a Source of Genetic Variability
Garcia-Ortiz MV, Marsin S, Arana ME, Gasparutto D, Guerois R, Kunkel TA, Radicella JP
2011
Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions
Fantini D, Vascotto C, Marasco D, D'Ambrosio C, Romanello M, Vitagliano L, Pedone C, Poletto M, Cesaratto L, Quadrifoglio F, Scaloni A, Radicella J P, Tell G
2010
Genetic dissection of Helicobacter pylori AddAB role in homologous recombination
Marsin S, Lopes A, Mathieu A, Dizet E, Orillard E, Guerois R, Radicella J P
2010
HO center dot radicals induce an unexpected high proportion of tandem base lesions refractory to repair by DNA glycosylases
Bergeron F, Auvre F, Radicella J P, Ravanat J L
2010
Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmium
Bravard A, Campalans A, Vacher M, Gouget B, Levalois C, Chevillard S, Radicella JP
2010
Oxidative stress triggers the preferential assembly of base excision repair complexes on open chromatin regions
Amouroux R, Campalans A, Epe B, Radicella JP
2010
Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina
Bigot K, Leemput J, Vacher M, Campalans A, Radicella JP, Lacassagne E, Provost A, Masson C, Menasche M, Abitbol M
2009
Oxidation status of human OGG1-S326C polymorphic variant determines cellular DNA repair capacity
Bravard A, Vacher M, Moritz E, Vaslin L, Hall J, Epe B, Radicella JP
2009
APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process
Vascotto C, Fantini D, Romanello M, Cesaratto L, Deganuto M, Leonardi A, Radicella JP, Kelley MR, D'Ambrosio C, Scaloni A, Quadrifoglio F, Tell G
2009
Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells
Eiberger W, Volkmer B, Amouroux R, Dhérin C, Radicella JP, Epe B
2008
Development of inducible systems to engineer conditional mutants of essential genes of Helicobacter pylori
Boneca IG, Ecobichon C, Chaput C, Mathieu A, Guadagnini S, Prévost MC, Colland F, Labigne A, de Reuse H
2008
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