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Publications du LRIG

Publié le 2 juillet 2018
  
Identification of key residues of the DNA glycosylase OGG1 controlling efficient DNA sampling and recruitment to oxidized bases in living cells
D’Augustin, O., Gaudon, V., Siberchicot, C., Smith, R., Chapuis, C., Depagne, J., Veaute, X., Busso, D., Di Guilmi, A.M., Castaing, B., Radicella, J.P., Campalans, A.*, Huet, S* (co-corresponding authors)
2023
A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner.
Ragu S, Droin N, Matos-Rodrigues G, Barascu A, Caillat S, Zarkovic G, Siberchicot C, Dardillac E, Gelot C, Guirouilh-Barbat J, Radicella JP, Ishchenko AA, Ravanat JL, Solary E, Lopez BS
2023
Foetal exposure to the bisphenols BADGE and BPAF impairs meiosis through DNA oxidation in mouse ovaries
Abdallah, S., Jampy, A., Moison, D., Wieckowski, M., Messiaen, S., Martini, E., Campalans, A., Radicella, JP., Rouiller-Fabre, V., Livera, G., Guerquin, MJ
2023
OGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression
Tanushi X., Pinna G., Vandamme M., Siberchicot C., D'Augustin O., Di Guilmi AM, Radicella JP., Castaing B., Smith R., Huet S., Leteurtre F.,  Campalans A.
2023
ComFC mediates transport and handling of single-stranded DNA during natural transformation
Prashant P Damke, Louisa Celma, Sumedha M Kondekar, Anne Marie Di Guilmi, Stéphanie Marsin, Jordane Dépagne, Xavier Veaute, Pierre Legrand, Hélène Walbott, Julien Vercruyssen, Raphaël Guérois, Sophie Quevillon-Cheruel, J Pablo Radicella
2022
Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein
Jacqueline Bernardino-Sgherri, Capucine Siberchicot, Frédéric Auvré, Didier Busso, Clémentine Brocas, Ghazi El Masri, Anna Lioutsko, Federica Ferri, J Pablo Radicella, Paul-Henri Romeo, Anne Bravard
2021
A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral shape to coccoids
Lamya El Mortaji, Alejandro Tejada-Arranz, Aline Rifflet, Ivo G. Boneca, Gerard Pehau-Arnaudet, J. Pablo Radicella, Stephanie Marsin and Hilde De Reuse
2020
Chromatin recruitment of OGG1 requires cohesin and mediator and is essential for efficient 8-oxoG removal.
Lebraud E, Pinna G, Siberchicot C, Depagne J, Busso D, Fantini D, Irbah L, Robeska E, Kratassiouk G, Ravanat JL, Epe B, Radicella JP, Campalans A
2020
Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?
Ostiane D'Augustin, Sébastien Huet, Anna Campalans, Juan Pablo Radicella 
2020
Human hematopoietic stem/progenitor cells display reactive oxygen species-dependent long-term hematopoietic defects after exposure to low doses of ionizing radiations
Elia Henry, Inès Souissi-Sahraoui, Margaux Deynoux, Andréas Lefèvre, Vilma Barroca, Anna Campalans, Véronique Ménard, Julien Calvo, Françoise Pflumio, Marie-Laure Arcangeli
2020
MasterPATH: network analysis of functional genomics screening data
Natalia Rubanova, Guillaume Pinna, Jeremie Kropp, Anna Campalans, Juan Pablo Radicella, Anna Polesskaya, Annick Harel-Bellan, Nadya Morozova
2020
Des mécanismes moléculaires Aux Applications Cliniques. L’essentiel Du Colloque Réplication-Réparation-Recombinaison 2019
2020
Lensless Microscopy Platform for Single Cell and Tissue Visualization
Ramona Corman, Willem Boutu, Anna Campalans, Pablo Radicella, Joana Duarte, Maria Kholodtsova, Laure Bally-Cuif, Nicolas Dray, Fabrice Harms, Guillaume Dovillaire, Samuel Bucourt, Hamed Merdji
2020
Molecular Dissection of Helicobacter Pylori Topoisomerase I Reveals an Additional Active Site in the Carboxyl Terminus of the Enzyme
Sumedha M Kondekar, Gaurav V Gunjal, Juan Pablo Radicella, Desirazu N Rao
2020
Changing surface grafting density has an effect on the activity of immobilized xylanase towards natural polysaccharides.
Montanier CY, Fanuel M, Rogniaux H, Ropartz D, Di Guilmi AM, Bouchoux A
2019
Correction to: Mutations in the nucleotide binding and hydrolysis domains of helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function.
Damke PP, Dhanaraju R, Marsin S, Radicella JP, Rao DN
2019
Identification of the periplasmic DNA receptor for natural transformation of Helicobacter pylori.
Damke PP, Di Guilmi AM, Fernández Varela P, Velours C, Marsin S, Veaute X, Machouri M, Gunjal GV, Rao DN, Charbonnier JB, Radicella JP.
2019
Prion protein deficiency impairs hematopoietic stem cells determination and sensitizes myeloid progenitors to irradiation
Siberchicot C, Gault N, Déchamps N, Barroca V, Aguzzi A, Roméo PH, Radicella JP, Bravard A, Bernardino-Sgherri J.
2019
Identification of an XRCC1 DNA binding activity essential for retention at sites of DNA damage
Mok MCY, Campalans A, Pillon MC, Guarné A, Radicella JP, Junop MS
2019
The C-terminal domain of HpDprA is a DNA-binding Winged Helix domain that does not bind double-stranded DNA.
Lisboa J, Celma L, Sanchez D, Marquis M, Andreani J, Guérois R, Ochsenbein F, Durand D, Marsin S, Cuniasse P, Radicella JP, Quevillon-Cheruel .
2019
Single Molecule Force Spectroscopy Reveals Two-Domain Binding Mode of Pilus-1 Tip Protein RrgA of Streptococcus pneumoniae to Fibronectin.
Becke TD, Ness S, Gürster R, Schilling AF, di Guilmi AM, Sudhop S, Hilleringmann M, Clausen-Schaumann H
2018
The transcription-coupled DNA repair-initiating protein CSB promotes XRCC1 recruitment to oxidative DNA damage.
Menoni H, Wienholz F, Theil AF, Janssens RC, Lans H, Campalans A, Radicella JP, Marteijn JA, Vermeulen W.
2018
Structural basis for the substrate selectivity of Helicobacter pylori NucT nuclease activity.
Celma L, Corbinais C, Vercruyssen J, Veaute X, de la Sierra-Gallay IL, Guerois R, Busso D, Mathieu A, Marsin S, Quevillon-Cheruel S, Radicella JP.
2017
Incorporating interaction networks into the determination of functionally related hit genes in genomic experiments with Markov random fields.
Robinson S, Nevalainen J, Pinna G, Campalans A, Radicella JP, Guyon L
2017
ComB proteins expression levels determine Helicobacter pylori competence capacity.
Corbinais C, Mathieu A, Damke PP, Kortulewski T, Busso D, Prado-Acosta M, Radicella JP, Marsin S.
2017
Laser microirradiation and temporal analysis of XRCC1 recruitment to single-strand breaks.
Campalans A, Radicella JP
2016
A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis
Saintigny Y, Chevalier F, Bravard A, Dardillac E, Laurent D, Hem S, Depagne J, Radicella JP2, Lopez BS
2016
Following transforming DNA in Helicobacter pylori from uptake to expression
Corbinais C, Mathieu A, Kortulewski T, Radicella JP, Marsin S
2016
Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function
Damke PP, Dhanaraju R, Marsin S, Radicella JP, Rao DN
2016
XPC deficiency is related to APE1 and OGG1 expression and function
de Melo JT, de Souza Timoteo AR, Lajus TB, Brandão JA, de Souza-Pinto NC, Menck CF, Campalans A, Radicella JP, Vessoni AT, Muotri AR,Agnez-Lima LF
2016
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